Aspergillus fumigatus spondylodiscitis with bilateral psoas abscess in a renal transplant patient with pulmonary tuberculosis : A rare case report

Authors

  • Ravikumar Tv MS Ramaiah Medical College , Bangalore,India
  • Raghvendra Rao MS Ramaiah Medical College , Bangalore,India
  • Amit Grover MS Ramaiah Medical College , Bangalore,India
  • Daksh Gadi MS Ramaiah Medical College , Bangalore,India

How to Cite

Tv, R., Rao, R., Grover, A., & Gadi, D. (2015). Aspergillus fumigatus spondylodiscitis with bilateral psoas abscess in a renal transplant patient with pulmonary tuberculosis : A rare case report. International Journal of Medicine, 3(2), 51-52. https://doi.org/10.14419/ijm.v3i2.4786

Received date: May 17, 2015

Accepted date: June 15, 2015

Published date: June 19, 2015

DOI:

https://doi.org/10.14419/ijm.v3i2.4786

Keywords:

Aspergillus, Psoas Abscess, Spondylodiscitis, Tuberculosis.

Abstract

Background: Aspergillus spondylodiscitis is increasingly described in immune-compromised patients. Its diagnosis is challenging and its delay results in high mortality and morbidity in view of its relative infrequency and the non- specific clinical signs and symptoms.

Case report:We report a case of thoracic spondylodiscitis caused by Aspergillus fumigatus in a patient of renal transplantation and with proven pulmonary tuberculosis.

Conclusion:We reiterate that transplantist and the treating physician should have high grade of suspicion for the invasive Aspergillosis even when the patient complains of vague non-specific back pain, and aggresively aim to rule out fungal infection. Early surgical debridement and antifungal therapy to be executedto prevent rapid progression of invasive aspergillosis and neurological damage.

References

  1. [1] Castelli C, Benazzo F, Minoli L, Marone P, Seghezzi R, Carlizzi CN. Aspergillus infection of the L3-L4 disc space in an immunosuppressed heart transplant patient. Spine (Phila Pa 1976). 1990; 15 (12):1369-1373. http://dx.doi.org/10.1097/00007632-199012000-00027.

    [2] ErsoyA.DizdarOA.OrucKocA,AkalinH.et al. Aspergillus Fumigatus Spondylodiskitis in Renal Transplant Patient: Voriconazole Experience ExpClinTransplant. 2011 Aug; 9 (4):265-9.

    [3] Gerlach UA, Kohler S, Sauer IM, et al. Aspergillus spondylodiscitis after multivisceral transplantation. Ann Transplant. 2009; 14 (4):52-57.

    [4] Hummel M, Schüler S, Weber U, et al. Aspergillosis with Aspergillus osteomyelitis and diskitis after heart transplantation: surgical and medical management. J Heart Lung Transplant. 1993; 12 (4):599-603.

    [5] Maschmeyer G, Haas A, Cornely OA. Invasive aspergillosis: epidemiology, diagnosis and management in immunocompromised patients. Drugs. 2007; 67 (11):1567-601. http://dx.doi.org/10.2165/00003495-200767110-00004.

    [6] Park SB, Kang MJ, Whang EA, Han SY, Kim HC. A case of fungal sepsis due to aspergillus spondydiscitis followed by cytomegalovirus infection in a renal transplant recipient. Transplant Proc. 2004; 36 (7):2154-2155. http://dx.doi.org/10.1016/j.transproceed.2004.08.049.

    [7] Rüping MJ, Vehreschild JJ, Cornely OA. Patients at high risk of invasive fungal infections: when and how to treat. Drugs. 2008; 68 (14):1941-62. http://dx.doi.org/10.2165/00003495-200868140-00002.

    [8] Salvalaggio PR, Bassetti M, Lorber MI, et al. Aspergillus vertebral osteomyelitis after simultaneous kidney-pancreas transplantation. Transpl Infect Dis. 2003; 5 (4):187-190. http://dx.doi.org/10.1111/j.1399-3062.2003.00030.x.

    [9] Tang TJ, Janssen HL, Van der Vlies CH, et al. Aspergillus osteomyelitis after liver transplantation: conservative or surgical treatment? Eur J GastroenterolHepatol. 2000; 12 (1):123-126. http://dx.doi.org/10.1097/00042737-200012010-00022.

    [10] Wéclawiak H, Garrouste C, Kamar N, et al. Aspergillus fumigatus-related spondylodiscitis in a heart transplant patient successfully treated with voriconazole. Transplant Proc. 2007; 39 (8):2627-2628. http://dx.doi.org/10.1016/j.transproceed.2007.08.014.

Downloads

How to Cite

Tv, R., Rao, R., Grover, A., & Gadi, D. (2015). Aspergillus fumigatus spondylodiscitis with bilateral psoas abscess in a renal transplant patient with pulmonary tuberculosis : A rare case report. International Journal of Medicine, 3(2), 51-52. https://doi.org/10.14419/ijm.v3i2.4786

Received date: May 17, 2015

Accepted date: June 15, 2015

Published date: June 19, 2015