Synthesis and Electrochemical Behavior of Some New Pyridazine Derivatives

Abstract

One-pot reaction of 1 with ethyl cyanoacetate and/or benzylidenemalono- nitrile afforded pyridazine derivatives 2 and 3, respectively. Compound 2 was subjected to some reactions to produce other new pyridazine derivatives. Also, treatment of 2 with hydrazine hydrate in ethanol gave the carbohydrazide 7. Some derivatives of the latter compound have been synthesized. Cyclic voltammograms of compounds 2, 5b, 7 and 8b using an undivided cell at platinum electrodes are discussed. The antimicrobial activity of some synthesized derivatives has been investigated.